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Normofem:
Powerful uterine tonic-restore rhythm of Menstual Cycle.
Pack Size: 100ml / 200ml. Sealed pack of 50 capsule. (Pilfer proof).
Dosage Form: Syrup / Capsule.
Indication: Specific
leucorrhoea, Dysmenorrhoea, lrregular Menstrual Cycle and eneral female
weakness, Menorrhagea, Post IUCD bleeding as astringent, Uterine tonic
and Cures Anaemia.
Dosage Syup: Two t.s.f. thrice a day. Or a directed by the physician.
Dosage Capsule: 1-2 Capsule thrice a day or as directed by the physician.
Composition: Each 10ml / 500m capsule contains std. ext.
Ashoka
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(Saraca indica)
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100 mg
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Udumbhar
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(Ficus glomerata)
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50 mg |
Lodhra
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(Symplocos racemosus)
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50 mg |
Hirabol
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(Balsmodendron myrrh)
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50 mg |
Shatavari
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(Asparagus racemosa)
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50 mg |
Vidarikhand
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(Dioscorea bulbifera)
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50 mg |
Tagarganth
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(VAlerian wallichi)
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50 mg |
Amita
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(Tinospora cordifolia)
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25 mg |
Shilajit
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(Asphaltam)
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25 mg |
Nagpushpa Yellow
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(Mesua ferrea)
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25 mg |
Yashtimadhu
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(Glycyrrhiza glabra)
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20 mg |
Compound Mixture of equal part of:
Apple (Pyrus mallus), Gajer (Dacus carota) Methi
(Trigonella foenum) Beet Root (Beta vulgarize) Glucose
Excipients.
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Pharmacological Actions
- Acts directly on the uterine muscles and fibres
- Astringent checks excess secretion
- Reduces hyperactivity of cervical glands
- Soothes and tones genito-urinary tract
- Corrects associated toublesome symptoms
- Control the infections and maintains the pH of the vagina
- Increase in female fetility and helps in conception.
Shatavri: Increases
the uterine weight. The saponin fraction of the extract exhibits
anti-oxytocic activity poducing a specific block of the pitocin induced
contractions of the spontaneous uterine motility.
Nagkesher: has
been found potentiating the alpha effects of adrenaline, relaxing the
smooth muscles, thereby exhibiting anti-oxytocic activity inhibition
against 5-HT induced conractions of the uterus. Nagkeshar also to its
calopyllide content reduces the increasing permeability in capillaries
and thus tones up the endometrial vascularity, thus checking excessive
bleeing and vaginal discharge.
In cases of
hypermenorrhoea, the relief with Lodhra due to its glycoside content
loturine, Collaturine and Loturidine was found to reduce the frequency
and intensity of contractions of both pregnant or non-pegnant uterus of
animals in in-vitra studies, thus reducing the probability of habitual
abortion. Lodhra is found to have estrogenic action on experimental
aminal uterus, due to its glucasidal content 3-monoglucoluronoside of
7-0 methyl leucopelagonidin, which is high astringent and is reported
to extert vasoconstrictor activity. A clinical study showed that
patient with continuous bleeding i.e. acyclical and cyclical had
significant relief within three days of Lodhra treatment.
The effect of
Ashoka compound preparation was noticed within three days. It was
observed that during the next cycle all the cases had normal
menstruation i.e. the bleeding was noraml for 4-5 days and devoid of
pain and uneasiness, throughout the three cycles. Haemoglobin status
was also up graded without the use of any other heamatinics. Ashoka is
found exerting stimulant effect on endometrial and ovaries due to its
tannins, catechols and flavonoid principles an dregulates excessive
hemorrhagic condition i.e. acyclical and cylical bleeding. The effects
are regulated by endogenous secretion possible by regulating the
Hypothalamus-Pituilary-Ovarian-Interactions.
Normofem capsule
/ syrup is claimed to act by stimulating the optimum functioning of
Hypothalamus-Pitultary-Ovarian-Axis. This helps in stimulation of
ovulation.
Normofem capsule
/ syrup aslso promotes normal endometrial proliferation. Thus this
pro-estrogenic agent provides benefits of efficacy similar to
otherdrugs used in the treatment ot intertility arising out of
ovulatory dysfunction, imbalance of Hypothalamus-Pituitary-Ovarian-Axi,
cervical mucus hostility, endometroisis or idiopathic.
Normofem capsule/syrup
shows an additional benefit in the from of normalizing the abnormal
menstrual parameters, which could have been the cause for unexplained
intertility.
Effect of Normofem Capsule/Syrup on Ovulatory Status
The
mechanism of action of Normofem capsule/syrup here is its proven
estrogenic activity, which could have added to the critical
pre-ovulatory blood concentration of estradiol to trigger mid cycle LH
surge. Further Normofem Capsule / syrup by the
Hypothalamus-Pituitary-Ovarian-Axis could have stimulated ovulation.
Effect of Normofem Capsule / Syrup on Conception
Normofem
Capsul / syrup aid conception by stimulating ovulation. The increased
endometrial glycogen content and inhibition of uterine hyper mobility
with Normofem capsule / syrup may have been responsible for proper
notation of blast cyst and continuation of further preganancy.
Effect of Normofem Capsule / Syrup on Menstrual Abnormalities
Patients
with irregular cycles are normalized with Normofem capsule/syrup due to
a better endometrial growth as a result of estrogenic activity either
directly of through Hypothalamus-Pilultary-Ovarian-Axis. Relief is also
obtained with Normofem capsule / syrup in hemorrhagic owing to
estrogenic activity. In hypomenorrhoea, estrogenic activity of Normofem
capsule / syrup is responsible for grwoth and thickness of endometrial
mucosa. Normofem capsule / syrup relieves patients from Dysmenorrhoea
by inhibiting the prostaglandin blosynthesis and curbing uterine
hypermotility. Among the ingredients present in Normofem capsul / Syrup
Ashoka has a stimulating effect on endometrial and ovarian tissue thus
providing a healthy environment for development of ovum and is a good
uterine sedative. Lodhra act to maintain the integrity of endometrium
and may thus protect the pregnancy. Shalavri has also been shown to
reduce excessive uterine contractions and thus play a vital role in
alleviating dysmenorrheal along with Nagkeshar and Shatavri provides
the respective nutrition.
100% Pure and natural herbal medicine.
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